Principal Architect

Amgen is seeking a Principal Architect to lead the design, development, and deployment of machine learning and Generative AI solutions, focusing on scalable data processing, architecture decisions, and cross-functional collaboration to impact patient care.

Location: Remote (US)

Salary: $144,423.50–$195,396.50/yr

Responsibilities

• Lead the end-to-end design, development, and delivery of machine learning and Generative AI (GenAI) solutions using Databricks, Apache Spark, SQL, and Python.
• Act as an architect for large-scale Data Engineering and ML/GenAI initiatives, driving architecture decisions across lakehouse platforms, distributed compute, and cloud ecosystems.
• Design and implement advanced data pipelines and AI systems, including batch and streaming data processing, data modeling, and ML workflows.
• Build and optimize robust data foundations for AI by developing high-quality, scalable ETL/ELT pipelines in Databricks.
• Define and institutionalize evaluation, validation, and governance frameworks for ML/GenAI systems.
• Partner with business stakeholders and product leaders to translate objectives into data-driven AI/ML solutions.
• Establish and enforce best practices in MLOps, LLMOps, DataOps, and DevOps.
• Architect and oversee scalable cloud-based data and AI platforms, integrating Databricks Lakehouse, Spark, and cloud-native services.
• Drive experimentation strategy, including A/B testing, prompt optimization, and data-driven iteration.
• Mentor L4 and L5 engineers in data engineering and AI/ML development.
• Lead cross-functional collaboration across data engineering, data science, platform engineering, and business teams.
• Stay at the forefront of advancements in data engineering and Generative AI/agentic systems.

Requirements

• Doctorate degree with 2 years of experience, OR Master’s degree with 4 years of experience, OR Bachelor’s degree with 6 years of experience, OR Associate’s degree with 10 years of experience, OR High school diploma / GED with 12 years of experience.

Benefits

• Comprehensive employee benefits package including health and welfare plans, retirement and savings plan, medical, dental, vision coverage, life and disability insurance, flexible spending accounts.
• Discretionary annual bonus or sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.

Additional Information

• Salary range in the U.S. is $144,423.50 to $195,396.50 annually.
• Application process is open until sufficient candidates are found.
• Sponsorship is not guaranteed.
• Amgen fosters an inclusive environment and is an Equal Opportunity employer. Reasonable accommodations are provided for individuals with disabilities.